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Menopause And Synthetic Ovaries

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Did you know that the first piece of advice we will offer is that the primary way to prevent heart disease are the steps that are recommended by the AHA and similar organizations, similar to smoking cessation, regular exercise, blood pressure control, and similar, said Levine. For those interested in meditation as an adjunctive step to decrease their risk of heart disease, we think that will be a reasonable thing to do as long as they understand that, now, we can say the data is suggestive but not definitive regarding meditation. The question is. Could Synthetic Ovaries Be Used to Treat Menopause?

Bioengineered organs could have been a brand new frontier for women’s health.

Some key questions still need to be answered. Human organs engineered in a lab could move from science fiction to fact soon. Researchers are investigating these organs as ways to treat various diseases and conditions, including menopause.

a tally new study examined the possibility of developing synthetic ovaries to treat symptoms associated with menopause and postmenopause. I know that the diminishment of key hormones put women at increased risk for heart disease and osteoporosis, right after ovaries stop functioning. Additionally, women face a host of symptoms that can be uncomfortable, just like hot flashes and vaginal dryness. Eventually, research released in the early 2000s found that HRT, given via patch or pills, could significantly increase the risk of certain cancers, heart disease, and stroke, while hormone replacement therapy can mitigate loads of these symptoms. Of this research, HRT has become less common and more controversial in recent years. Keep reading. Many women receive no HRT after reaching menopause, or are put on much smaller doses of hormones. Essentially, due to these risks, doctors and researchers been looking for newer, safer options to provide women with replacement hormones. One possibility might be implanting synthetic ovaries.

These engineered organs better mimic real ovaries and provide the hormones at lower doses. Woman’s menopause symptoms can hereafter be diminished without increasing the risk of cancer and heart disease. Researchers from the Wake Forest Institute for Regenerative Medicine were able to create biosynthetic ovaries to implant in rats to see if they could mitigate some menopause symptoms. They isolated two cells contained in the ovary called the theca and the granulosa. Conforming to their study published earlier this month in Nature Communications, they managed to encapsulate them into a thin engineered membrane and implant them into the rats. Of course, the ovary did not make eggs that should result in the rats becoming fertile. Certainly, opara and his ‘co authors’ found that the rats with the engineered ovaries appeared to have better bone mineral density than the rats that received the equivalent of low hormone therapy replacement. That is interesting right? It was also about equal to the rats that had high doses of HRT. With that said, this finding was notable since the quantity of hormones released in these rats was far lower than in both the highlevel and ‘lowlevel’ HRT rats. Known the rats with the synthetic ovaries also had less weight gain and their uteruses were not as large as the rats that had both low and high doses of HRT.

That said, this study highlights the potential utility of ‘cellbased’ hormone therapy for the treatment of conditions associated with the loss of ovarian function, said Opara. Accordingly the research is still in the early stages. It will take more time and research before a longterm synthetic ovary could’ve been considered a treatment option for postmenopausal women. With that said, this study does provide a really new avenue of research, that is key to finding better ways to New York City, called the study absolutely transformational. He said that in spite the fact that this research is in the early stages, patients was left without many choices of treatment if they don’t pursue HRT. That has really caused a cr that ain’t much discussed, he said. That’s a fact, it’s a major problem for women. Besides, they don’t have a replacement. They don’t have anything else. He pointed out that ‘non HRT’ treatments are less effective at keeping bones healthy for postmenopausal women.

You can give her calcium, you can give her magnesium…You can give her weight bearing exercises, he said. They are not as good as estrogen. Hershlag said the possibility of synthetic ovaries could potentially mean a ‘longterm’ treatment for menopause symptoms while not increasing the risk of other conditions like heart disease. However. Tanmoy Mukherjee, assistant professor of obstetrics, gynecology, and reproductive medicine at the Icahn School of Medicine and co director of Reproductive Medicine Associates of NYC, said this research was definitely exciting. With all that said… Experts certainly been waiting for some kind of hormone replacement therapy that is safe, that’s effective, he ld Healthline.

Actually the right hormones are important for bone health, cardiac health, cognitive function, So there’re multiple effects of estrogen. He also said mostly there’re many questions that need answering before the synthetic ovaries will be considered as an experimental treatment for women, while Mukherjee said he was excited about the findings. So that’s what research is all about, in my opinion it’s exciting but I reckon there are the questions that have to be addressed before it can be widely utilized, he said. Anyways, for a while the device should work and whether it would’ve been safer than the current ‘low dose’ HRT. It’s hard enough to remind people to take a pill every day, let alone come in for an implantable kind of hormone therapy, he said. Fact, he called the surgical implantation a big stumbling block.

 


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