Niacinamide has been cited in two different studies as a well-tolerated treatment. Wake Forest University researchers evaluated 50 subjects with rosacea. Their study, which was released in the August 2005 issue of “Cutis,” discovered that applying a niacinamide-based moisturizer to the face and lower arm twice daily for 4 weeks relieved signs of the condition. The University of Pittsburgh’s Nicomide Enhancement in Clinical Results Research study, or NICOS, showed comparable outcomes. The majority of research study participants reported enhanced midway through the eight-week study 79 percent reported their appearance to be either reasonably or better, while 55 percent showed a moderate to significant reduction in rosacea sores.
When vitamin B3, or niacin, combines with amino acids of another particle, the chemical reaction produces niacinamide, also referred to as nicotinamide or nicomide. The majority of people get a day-to-day advised allowance of vitamin B3 through the intake of nuts, fish, strengthened breads and cereals, and multivitamins, but inning accordance with the Pharmacy Mix blog site, it is most effective in the treatment of skin problem when used topically.
Reinforcing the external layer of skin is a major home of niacinamide. Vitamin B3 offers a fuel which reinforces cellular bonds and tightens up skin. As a result of this tightening up, acne has a tougher time taking root. A 2004 study in the “Journal of Cosmetic Dermatology” confirms this declaration. The German scientists found the stabilization of the skin’s external layer has an anti-inflammatory effect, which can prevent acne breakouts. The abovementioned NICOS report takes this an action even more, as acne clients recognized similar benefits as those with rosacea.
Countless dollars are spent each year on cosmetics, medications and treatments to obtain rid of wrinkles and great lines on the face, the most apparent indication of aging skin. A team of Japanese dermatologists studied niacinamide’s effectiveness on 30 females who had wrinkles in the eye area. Topics received a 4 percent niacinamide cream on one side of their face and a topical without any nutrients on the other. In 64 percent of test participants, wrinkles in the eye location were minimized. The research study, published in a 2008 edition of the “Journal of Dermatology,” showed that only one person had a problem with the niacinamide cream, reporting “minimal irritation.” The research study concluded that the niacinamide cream was “well endured and might be an optional preparation” for wrinkle treatment.
Reference to: http://www.livestrong.com/